Szoptatás és allergia

Breastfeeding and atopic dermatitis: protective or harmful? facts and controversies

Alan M. Dattner MD
Clinics in Dermatology Volume 28, Issue 1, January 2010, Pages 34-37

Abstract

Conventional wisdom posits that breastfeeding during the first 4 months of life generally reduces the incidence of atopic dermatitis in the child. Recent studies question this truism, especially in cases when the mother herself is allergic.

Breastfeeding and the prevalence of allergic diseases in schoolchildren: Does reverse causation matter?

Kusunoki T, Morimoto T, Nishikomori R, Yasumi T, Heike T, Mukaida K, Fujii T, Nakahata T.
Pediatr Allergy Immunol. 2010 Jan 14.

Abstract

Infants at higher risk of allergic diseases might be breastfed for longer periods compared with infants at lower risk in the hope that breastfeeding might reduce the risk of atopic disorders. Therefore, this intention could manifest as an apparent allergy-promoting effect of breastfeeding or reverse causation.

Effects of Early Nutritional Interventions on the Development of Atopic Disease in Infants and Children

Frank R. Greer, MD, Scott H. Sicherer, MD, A. Wesley Burks, MD and the Committee on Nutrition and Section on Allergy and Immunology

PEDIATRICS Vol. 121 No. 1 January 2008, pp. 183-191

Abstract

This clinical report reviews the nutritional options during pregnancy, lactation, and the first year of life that may affect the development of atopic disease (atopic dermatitis, asthma, food allergy) in early life. It replaces an earlier policy statement from the American Academy of Pediatrics that addressed the use of hypoallergenic infant formulas and included provisional recommendations for dietary management for the prevention of atopic disease.

Immunomodulatory constituents of human milk change in response to infant bronchiolitis

Dani-Louise Bryan, Prue H. Hart, Kevin D. Forsyth, Robert A. Gibson (2007)
Pediatric Allergy and Immunology 18 (6), 495–502

Abstract

Although epidemiological evidence is generally supportive of a causal association between respiratory syncytial virus (RSV) bronchiolitis during infancy and the development of persistent wheeze/asthma, if not allergy, the mechanism by which this occurs and an explanation for why all children do not succumb remains to be elucidated. Breast feeding has been found to confer a protective effect against respiratory infections such as RSV bronchiolitis and allergy; however, again there is little direct evidence and no clear mechanism. In this study, we examined whether human milk immunomodulatory factors (cells, cytokines) change in response to clinically diagnosed, severe bronchiolitis in the recipient breast-fed infant.

Breastfeeding and Maternal and Infant Health Outcomes in Developed Countries

Stanley Ip, M.D., Mei Chung, M.P.H., Gowri Raman, M.D., Priscilla Chew, M.P.H., Nombulelo Magula, M.D., Deirdre DeVine, M.Litt., Thomas Trikalinos, M.D., Ph.D., Joseph Lau, M.D.

Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services, April 2007

Structured Abstract

Objectives: We reviewed the evidence on the effects of breastfeeding on short- and long-term infant and maternal health outcomes in developed countries.

Data Sources: We searched MEDLINE®, CINAHL, and the Cochrane Library in November of 2005. Supplemental searches on selected outcomes were searched through May of 2006. We also identified additional studies in bibliographies of selected reviews and by suggestions from technical experts.

Food allergy and the introduction of solid foods to infants: a consensus document

Alessandro Fiocchi MD; Amal Assa'ad MD; Sami Bahna MD

Annals of Allergy, Asthma and Immunology 2006, vol. 97, no. 1, pp. 10 - 21

Abstract

Objective: To make recommendations based on a critical review of the evidence for the timing of the introduction of solid foods and its possible role in the development of food allergy.

Data Sources: MEDLINE searches using the following search algorithm: [weaning AND infant AND allergy]/[food allergy AND sensitization]/[dietary prevention AND food allergy OR allergens]/[Jan 1980-Feb 2006].

Study Selection: Using the authors' clinical experience and research expertise, 52 studies were retrieved that satisfied the following conditions: English language, journal impact factor above 1 or scientific society, expert, or institutional publication, and appraisable using the World Health Organization categories of evidence.

Vitamin C in breast milk may reduce the risk of atopy in the infant

U Hoppu, M Rinne, P Salo-Väänänen, A-M Lampi, V Piironen and E Isolauri

European Journal of Clinical Nutrition (2005) 59, 123−128

Abstract

Objective: To assess the effects of maternal dietary and supplement intake of vitamins C and E on breast milk antioxidant composition (vitamin C, alpha-tocopherol and beta-carotene) and their protective potential against the development of atopy in the infant.

The association of prolonged breastfeeding and allergic disease in poor urban children

C. C. Obihara, B. J. Marais, R. P. Gie1, P. Potter, E. D. Bateman, C. J. Lombard, N. Beyers and J. L. L. Kimpen

Eur Respir J 2005; 25:970-977

The fact that breastfeeding may protect against allergic disease remains controversial, with hardly any reports from developing countries. This study investigated the association between allergic disease in children and prolonged breastfeeding.

Infant growth and health outcomes associated with 3 compared with 6 mo of exclusive breastfeeding

Michael S Kramer, Tong Guo, Robert W Platt, Zinaida Sevkovskaya, Irina Dzikovich, Jean-Paul Collet, Stanley Shapiro, Beverley Chalmers, Ellen Hodnett, Irina Vanilovich, Irina Mezen, Thierry Ducruet, George Shishko and Natalia Bogdanovich

American Journal of Clinical Nutrition, Vol. 78, No. 2, 291-295, August 2003

Abstract

Background: Opinions and recommendations about the optimal duration of exclusive breastfeeding have been strongly divided, but few published studies have provided direct evidence on the relative risks and benefits of different breastfeeding durations in recipient infants.

Objective: We examined the effects on infant growth and health of 3 compared with 6 mo of exclusive breastfeeding.

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