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Monika Østensen; Mario Motta

Nature Clinical Practice Rheumatology 2007 Jul;3(7):400-6. Review.

Summary

In 90% of cases, women with rheumatoid arthritis suffer a disease flare within 3 months of delivery of their baby. Drug treatment is, therefore, required; however, such therapies have implications for mothers who decide to nurse their infants. Unfortunately, because of a paucity of data, little is known about the transfer of antirheumatic drugs into breast milk, and even less is known about whether small amounts of these agents ingested during nursing could harm the infant. Our review of the literature indicates that paracetamol, prednisone, antimalarial agents, sulfasalazine and most NSAIDs can safely be used by lactating mothers.

Katherine K. Temprano, MD, Rama Bandlamudi, MD, Terry L. Moore, MD

Semin Arthritis Rheum. 2005 Oct;35(2):112-21

OBJECTIVE: To review the toxicity issues of commonly used antirheumatic drugs in pregnancy and lactation.

METHODS: A review of the medical literature using Medline database via Ovid was performed to identify the toxicities of antirheumatic drugs in pregnancy and lactation.