Antipszichotikumok

Lithium in Breast Milk and Nursing Infants: Clinical Implications

Adele C. Viguera, M.D., M.P.H., D. Jeffrey Newport, M.D., James Ritchie, Ph.D., Zachary Stowe, M.D., Theodore Whitfield, Sc.D., Juliana Mogielnicki, B.A., Ross J. Baldessarini, M.D., Amanda Zurick, B.A. and Lee S. Cohen, M.D.

Am J Psychiatry 164:342-345, February 2007

Abstract

OBJECTIVE: Current practice guidelines discourage use of lithium during breast-feeding, despite limited data. This study aimed to quantify lithium exposure in nursing infants.

METHOD: In 10 mother-infant pairs, the authors obtained assays of lithium in maternal serum, breast milk, and infant serum and indices of infant renal and thyroid function.

WHEN BREASTFEEDING MOTHERS NEED CNS-ACTING DRUGS

Evelyn T. Rubin, Amy Lee, Shinya Ito

Can J Clin Pharmacol Vol 11(2) Fall 2004: e257-e266;

ABSTRACT

Background Breastfeeding is the ideal method of infant nutrition. However, if mothers need medications such as the central nervous system (CNS) acting drugs, infant safety concerns arise. Summarized information on infant exposure levels to drugs in milk and associated side effect profiles will help clinicians to rationalize and justify important drug therapy for a breastfeeding patient.

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