Administration of Contrast Media to Breast-Feeding Mothers

Administration of either an iodinated or a gadolinium- based contrast media occasionally is indicated for an imaging study on a woman who is breast-feeding. Both the patient and the patient’s physician may have concerns regarding potential toxicity to the infant from contrast media that is excreted into the breast milk.

The literature on the excretion into breast milk of iodinated and gadolinium-based contrast media and the gastrointestinal absorption of these agents from breast milk is very limited however, several studies have shown that less than 1% of the administered maternal dose of contrast medium is excreted into breast milk; and less than 1% of the contrast medium in breast milk ingested by an infant is absorbed from the gastrointestinal tract. Therefore, the expected dose of contrast medium absorbed by an infant from ingested breast milk is extremely low.

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